Calcitonin Antibody

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Product Details

Summary
Reactivity Hu, Mu, Rt, Ma, RbSpecies Glossary
Applications WB, ICC/IF, IHC
Clonality
Polyclonal
Host
Sheep
Conjugate
Unconjugated

Order Details

Calcitonin Antibody Summary

Immunogen
Synthetic peptide corresponding to a portion of rat alpha-calcitonin gene-related peptide (CGRP).
Localization
Secreted
Clonality
Polyclonal
Host
Sheep
Gene
CALCA
Purity
IgG purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:200-1:4000
  • Western Blot
Application Notes
Use in WB and ICC/IF reported in scientific literature (PMID: 21491428). Test tissues: Rat thoracolumbar spinal cord. Fixatives: Recommended fixative is 4% formaldehyde (prepared from para-polymer) in 0.1M sodium phosphate buffer (pH 7.2-7.4). Perfusion fixation is recommended if possible.
Control
CXXC1 Overexpression Lysate
Publications
Read Publication using
NB600-1156 in the following applications:

Reactivity Notes

Gerbil reactivity reported in scientific literature (PMID: 21491428). Likely to react with other mammalian species (based on homology, not tested).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Purity
IgG purified

Alternate Names for Calcitonin Antibody

  • ATP2B2plasma membrane calcium ATPase
  • ATPase, Ca++ transporting, plasma membrane 4
  • CALC1
  • CALCA
  • Calcitonin
  • DKFZp686G08106
  • DKFZp686M088
  • EC 3.6.3
  • EC 3.6.3.8
  • Katacalcin
  • Matrix-remodeling-associated protein 1
  • matrix-remodelling associated 1
  • MXRA1
  • PCT
  • Plasma membrane calcium ATPase isoform 4
  • Plasma membrane calcium pump isoform 4
  • plasma membrane calcium pump
  • plasma membrane calcium-transporting ATPase 4
  • PMCA4b
  • PMCA4PMCA4x
  • sarcolemmal calcium pump

Background

CGRP is present in C-cells of the thyroid and in central and peripheral nerves. CGRP has several important physiologic roles: it is a potent vasodilator, and can affect the force and rate of heart beat; it can modulate acetylcholine receptor function at the neuromuscular junction; it has been demonstrated to block tolerance to morphine; and it can modulate antigen presentation in Langerhans cells in the skin. Despite these important physiologic functions, therapeutic strategies using CGRP have been impeded due to the lack of a cloned CGRP receptor with which ligands could be developed.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Calcitonin Antibody (NB600-1156)(1)

We have publications tested in 1 confirmed species: Gerbil.

We have publications tested in 3 applications: ICC/IF, IF/IHC, WB.


Filter By Application
ICC/IF
(1)
IF/IHC
(1)
WB
(1)
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Filter By Species
Gerbil
(1)
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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for Calcitonin Antibody (NB600-1156) (0)

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Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CALCA
Entrez
Uniprot