Cadherin-11 Antibody

Images

 
Western Blot: Cadherin-11 Antibody [NBP1-52046] - HEK293 lysate (10ug protein in RIPA buffer) overexpressing Human CDH11 with C-terminal MYC tag probed with this antibody (1ug/ml) in Lane A and probed with anti-MYC Tag ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, PEP-ELISA
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

Cadherin-11 Antibody Summary

Immunogen
Peptide with sequence CESDQTKPLSNQP corresponding to internal region according to NP_001788.2.
Epitope
CESDQTKPLSNQP
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
CDH11
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 0.1 - 0.5 ug/ml
  • Peptide ELISA Detection limit 1:8000
Application Notes
WB: In transfected HEK293 transiently expressing full-length human CDH11 (myc and DYKDDDDK tagged), a band of approx. 130 kDa band was observed. No bands were observed in mock-transfected HEK293 and the same band was observed using anti-myc tag antibody.
Publications
Read Publication using NBP1-52046.

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Rat, Canine, Bovine.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Cadherin-11 Antibody

  • CAD11OSF-4
  • cadherin 11, type 2, OB-cadherin (osteoblast)
  • Cadherin11
  • Cadherin-11
  • CDH11
  • CDHOB
  • OB
  • OB-Cadherin
  • Osteoblast cadherin

Background

This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Cadherin-11 Antibody (NBP1-52046)(1)

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CDH11
Entrez
Uniprot