CACNA1I Antibody - BSA Free

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

CACNA1I Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit CACNA1I Antibody - BSA Free (NBP3-30955) is a polyclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Synthetic peptide derived from the rat CACNA1I conjugated to KLH
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CACNA1I
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot : 1:400
• Application Notes: .

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Phosphate buffered saline
• Preservative: 0.08% Sodium Azide
• Purity: Antigen Affinity-purified

Alternate Names for CACNA1I Antibody - BSA Free

• Ca(v)3.3
• CACNA1I
• calcium channel, voltage-dependent, T type, alpha 1I subunit
• KIAA1120
• voltage-dependent T-type calcium channel subunit alpha-1I
• voltage-dependent, alpha 1I subunit
• Voltage-gated calcium channel subunit alpha Cav3.3

Background

Function: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. Isoform alpha-1I gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite negative potentials, and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes. Gates in voltage ranges similar to, but higher than alpha 1G or alpha 1H.; Subcellular location: Membrane; Multi-pass membrane protein.; Tissue specificity: Brain specific

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CACNA1I