CACNA1I Products

Antibodies
CACNA1I Antibody
CACNA1I Antibody
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-Fr, IHC-P
Host: Rabbit Polyclonal
CACNA1I Antibody (2F5)
CACNA1I Antibody (2F5)
H00008911-M01
Species: Hu
Applications: WB, ELISA
Host: Mouse Monoclonal
CACNA1I Antibody (3H5)
CACNA1I Antibody (3H5)
H00008911-M02
Species: Hu
Applications: WB, ELISA
Host: Mouse Monoclonal
Proteins
Recombinant Human CACNA1I Pro ...
Recombinant Human CACNA1I Protein
H00008911-Q01
Species: Hu
Applications: WB, ELISA, PA
RNAi
CACNA1I RNAi
CACNA1I RNAi
H00008911-R01
Species: Hu
Applications: RNAi, RNAi SP
CACNA1I RNAi
CACNA1I RNAi
H00008911-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

Function: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. Isoform alpha-1I gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite negative potentials, and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes. Gates in voltage ranges similar to, but higher than alpha 1G or alpha 1H.; Subcellular location: Membrane; Multi-pass membrane protein.; Tissue specificity: Brain specific

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Product By Gene ID 8911
Alternate Names
  • Ca(v)3.3
  • voltage-dependent T-type calcium channel subunit alpha-1I
  • Voltage-gated calcium channel subunit alpha Cav3.3
  • voltage-dependent, alpha 1I subunit
  • calcium channel, voltage-dependent, T type, alpha 1I subunit

Pathways for CACNA1I

View related products by pathway and learn more about each of the pathways below.

Localization
Cell Adhesion
Parturition
Acrosome Reaction
Fertilization
Glycosylation
Pathogenesis

PTMs for CACNA1I

Learn more about PTMs related to CACNA1I.

Glycosylation

Bioinformatics Tool for CACNA1I

Discover related pathways, diseases and genes to CACNA1I. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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