C1qTNF3/CORS26/CTRP3 Antibody [Janelia Fluor® 525]

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, ICC/IF, IHC, ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Janelia Fluor 525

C1qTNF3/CORS26/CTRP3 Antibody [Janelia Fluor® 525] Summary

• Immunogen: Antibody was raised against a peptide corresponding to 16 amino acids near the center of human C1qTNF3/CORS26/CTRP3. The immunogen is located within amino acids 90-140 of C1qTNF3/CORS26/CTRP3. Amino Acid Sequence: PRGERGQHGPKGEKGY
• Specificity: Multiple isoforms of C1qTNF3/CORS26/CTRP3 are known to exist. C1qTNF3/CORS26/CTRP3 antibody is predicted to not recognize other members of the CTRP protein family. Human C1qTNF3/CORS26/CTRP3 has 3 isoforms, including isoform 1 (246aa, 27kD), isoform 2 (198aa, 22kD) and isoform 3 (319aa, 35kD). Mouse C1qTNF3/CORS26/CTRP3 has one isoform (246aa, 27kD) and Rat C1qTNF3/CORS26/CTRP3 also has one isoform (319aa, 35kD). NBP1-76628 can detect human, mouse and rat.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: C1QTNF3
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Peptide affinity purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for C1qTNF3/CORS26/CTRP3 Antibody [Janelia Fluor® 525]

• C1ATNF3
• C1q and tumor necrosis factor related protein 3
• C1qTNF3
• Cartducin
• cartonectin
• collagenous repeat-containing sequence of 26-kDa
• complement C1q tumor necrosis factor-related protein 3
• complement-c1q tumor necrosis factor-related protein 3
• Corcs
• Cors
• CORS26
• Cors-26
• CTRP3
• CTRP32310005P21Rik
• FLJ37576
• Secretory protein CORS26

Background

Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. Multiple isoforms of human CTRP3 have been reported. It has been suggested that CTRP3 may play a role in skeletal development.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: C1QTNF3