C1qTNF3/CORS26/CTRP3 Products

Description

Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. Multiple isoforms of human CTRP3 have been reported. It has been suggested that CTRP3 may play a role in skeletal development.

Bioinformatics

Product By Gene ID	114899
Alternate Names	C1ATNF3 C1q and tumor necrosis factor related protein 3 C1qTNF3 Cartducin cartonectin collagenous repeat-containing sequence of 26-kDa complement C1q tumor necrosis factor-related protein 3 complement-c1q tumor necrosis factor-related protein 3 Corcs Cors CORS26 Cors-26 CTRP3 CTRP32310005P21Rik FLJ37576 Secretory protein CORS26

Research Areas for C1qTNF3/CORS26/CTRP3

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Signal Transduction