C1qR1/CD93 Antibody (273107) [Alexa Fluor™ Plus 405]

• Reactivity: Hu
• Clone: 273107
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 405

C1qR1/CD93 Antibody (273107) [Alexa Fluor™ Plus 405] Summary

• Specificity: Detects human C1q R1/CD93 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross‑reactivity with recombinant mouse C1q R1 is observed.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for C1qR1/CD93 Antibody (273107) [Alexa Fluor™ Plus 405]

• AA4 Antigen
• C1q R1
• C1q receptor 1
• C1q Rp
• C1q/MBL/SPA receptor
• C1qR(P)
• C1qR1
• C1qRp
• CD93 antigenC1qR
• CD93 molecule
• CD93
• CDw93C1QR1
• Collectin Receptor
• Complement component 1 q subcomponent receptor 1
• complement component 1, q subcomponent, receptor 1
• complement component C1q receptor
• dJ737E23.1
• ECSM3
• Ly68
• Matrix-remodeling-associated protein 4
• matrix-remodelling associated 4
• MXRA4

Background

C1q R1 is also known as C1q Rp, Collectin Receptor, and AA4 antigen, and is designated CD93. C1q R1 mediates enhanced phagocytosis by monocytes and macrophages upon interaction with soluble defense collagens including C1q, MBL, and SP-A (1, 2). It is a type I transmembrane glycoprotein expressed on endothelial cells, hematopoietic progenitor cells, platelets, and cells of myeloid origin. C1q R1 has also been identified as a stem cell marker (3, 4).

1. Kim, T.S. et al. (2000) Mol. Immunol. 37:377.
2. Dean, Y.D. et al. (2001) Eur. J. Immunol. 31:1370.
3. Petrenko, O. et al. (1999) Immunity 10:691.
4. Danet, G.H. et al. (2002) Proc. Natl. Acad. Sci. USA 99:10441.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.