c-Rel Antibody

Images

 
Western Blot: c-Rel Antibody [NBP1-52021] - Analysis of c-Rel in Human Spleen lysate (35ug protein in RIPA buffer) using this antibody at 0.5 ug/ml. Primary incubation was 1 hour. Detected by chemiluminescence.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, PEP-ELISA
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated

Order Details

c-Rel Antibody Summary

Immunogen
Peptide with sequence NDLNASNACIYN corresponding to internal region according to NP_002899.1.
Epitope
NDLNASNACIYN
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
REL
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 0.5 - 2 ug/ml
  • Peptide ELISA Detection limit 1:16000
Application Notes
WB: Approx. 70 kDa band observed in human spleen and human peripheral blood mononucleocytes lysates (calculated MW of 68.5 kDa band according to NP_002899.1).
Publications
Read Publication using NBP1-52021.

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Canine.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for c-Rel Antibody

  • C-Rel proto-oncogene protein
  • cRel
  • c-Rel
  • I-Rel
  • oncogene REL, avian reticuloendotheliosis
  • proto-oncogene c-Rel
  • REL
  • v-rel avian reticuloendotheliosis viral oncogene homolog
  • v-rel reticuloendotheliosis viral oncogene homolog (avian)

Background

c Rel is a protooncogene encoding a subunit of the NF kappa B family of transcription factors. In B and T cells, it is involved in the regulation of genes controlling cell division and immune function.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for c-Rel Antibody (NBP1-52021)(1)

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for c-Rel Antibody (NBP1-52021)

Discover related pathways, diseases and genes to c-Rel Antibody (NBP1-52021). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Blogs on c-Rel.

NFkB and p62 Both Activate and Regulate Inflammation
Nuclear factor kappa-light-chain-enhancer of activated B cells (NFkB) is a protein complex that regulates DNA transcription and is a critical regulator of cell survival. NFkB has long been known as a primer of inflammation, however researchers are...  Read full blog post.

RelA/NF-kB - A proinflammatory signaling pathway with roles in immunity and cancer
The inflammatory response consists of a complex network of signaling pathways that regulate a diverse set of cytokines, growth factors, adhesion molecules, and transcription factors (1). Of the proinflammatory signaling pathways the NF-kB family is...  Read full blog post.

Nuclear Factor kappa B Signaling in the Immune System
Nuclear Factor kappa B (NFkB) binds to the kappa-beta site of the immunoglobulin kappa light chain gene enhancer. Thus NFkB has become one of the widely studied transcription factors in innate and adaptive immune responses. The NFkB family is composed...  Read full blog post.

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Bioinformatics

Gene Symbol REL
Entrez
Uniprot