C-Reactive Protein/CRP Antibody (232026) [Unconjugated]

Western blot shows lysates of human kidney tissue. PVDF membrane was probed with 0.5 µg/mL of Mouse Anti-Human/Mouse/Porcine C-Reactive Protein/CRP Monoclonal Antibody (Catalog # MAB1707) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF018). A specific band was detected for C-Reactive Protein/CRP at approximately 25 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

• Reactivity: Hu, Mu, Po
• Applications: WB
• Clone: 232026
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Concentration: LYOPH

C-Reactive Protein/CRP Antibody (232026) [Unconjugated] Summary

• Immunogen: Human plasma-derived CRP
• Specificity: Detects rhCRP in direct ELISAs and Western blots. In direct ELISAs and Western blots, this antibody shows 100% cross-reactivity with rmCRP and rpCRP but no cross-reactivity with rrCRP.
• Source: N/A
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: CRP
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot 0.5 ug/mL

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for C-Reactive Protein/CRP Antibody (232026) [Unconjugated]

• C-Reactive Protein
• C-reactive protein, pentraxin-related
• CRP
• MGC88244
• pentraxin 1
• PTX1MGC149895

Background

CRP is a secreted protein that belongs to the Pentraxin family. It circulates as a non-covalent homopentamer. The CRP concentration in human plasma is highly increased during acute phase response to tissue injury or infection.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for C-Reactive Protein/CRP Antibody (MAB1707)(1)

Publication using MAB1707

• Human galectin 3 binding protein interacts with recombinant adeno-associated virus type 6. J. Virol., 2012-04-11;86(12):6620-31. 2012-04-11 [PMID: 22496229] (Western Blot, Human)

Bioinformatics

• Gene Symbol: CRP