c-Maf Antibody [Biotin]

• Reactivity: Hu, Mu, Rt, Bv, Pm
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Biotin

c-Maf Antibody [Biotin] Summary

• Description: This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
  
  For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
• Immunogen: A synthetic peptide corresponding to amino acids 75-110 of human c-maf was used as the immunogen, GenBank no. NP_001026974.1|.
• Specificity: 100% homologous in human isoforms CRA_a, CRA_b, and CRA_c).
• Predicted Species: Monkey (93%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: MAF
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Recommended applications are based on validated applications from the unconjugated base product NBP2-24551. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Reactivity Notes

Chimpanzee (87%), Bovine, Equine (81%).

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for c-Maf Antibody [Biotin]

• Avian musculoaponeurotic fibrosarcoma (MAF) protooncogene
• CCA4
• c-maf proto-oncogene
• cMaf
• c-Maf
• MAF2
• MGC71685
• Proto-oncogene c-Maf
• T lymphocyte c-maf long form
• transcription factor Maf
• v-maf musculoaponeurotic fibrosarcoma (avian) oncogene homolog
• v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)
• V-maf musculoaponeurotic fibrosarcoma oncogene homolog

Background

c-Maf is part of the Maf family of transcription factors that possess a conserved basic region and a leucine zipper domain that mediate DNA and protein-protein binding and plays an important role in tissue-specific gene regulation and cell differentiation. c-Maf is a transcriptional activator of interleukin 4 and 10 in T-cells, and is involved in lens fiber cell differentiation. c-Maf translocation has been observed in human multiple myeloma and may be oncogenic.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MAF