BMX Antibody (1C6)

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Western Blot: BMX Antibody (1C6) [NBP1-47489] - Western blot analysis using BMX mAb against BMX-hIgGFc transfected HEK293 cell lysate.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clone
1C6
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

BMX Antibody (1C6) Summary

Immunogen
Purified recombinant fragment of human BMX expressed in E. Coli.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
BMX
Purity
Unpurified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:2000
  • ELISA 1:10000
Theoretical MW
78 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Hunam

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Ascites
Preservative
0.03% Sodium Azide
Purity
Unpurified

Alternate Names for BMX Antibody (1C6)

  • BMX non-receptor tyrosine kinase
  • BMX
  • Bone marrow tyrosine kinase gene in chromosome X protein
  • EC 2.7.10
  • EC 2.7.10.2
  • Epithelial and endothelial tyrosine kinase
  • ETK
  • Etk/Bmx cytosolic tyrosine kinase
  • ETKcytoplasmic tyrosine-protein kinase BMX
  • NTK38 tyrosine kinase
  • NTK38
  • PSCTK2
  • PSCTK3

Background

Etk (epithelial and endothelial tyrosine kinase) is a member of the TEC family of non-receptor protein tyrosine kinase which includes Btk, Itk and TEC. Etk is composed of a pleckstrin domain, an SH3 and SH2 domain and a catalytic kinase domain (1). Etk is implicated in cell adhesion, migration, proliferation, survival as well as signal transduction (2). In PCA, Etk activation by IL-6 is mediated by PI3-K (3). It as also been shown in TNF-induced angiogenesis, TNF activates Etk through TNFR2 (4). Additionally, in the AR pathway, ETtk, FAK and Src form a complex. FAK activates Src which in turn activates Etk by phosphorylating Etk tyrosine residue 566 (5).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol BMX
Entrez