BMX Products

Antibodies
BMX Antibody
BMX Antibody
AF5887
Species: Hu
Applications: WB, IHC
Host: Sheep Polyclonal
BMX Antibody (3G3)
BMX Antibody (3G3)
H00000660-M01
Species: Hu
Applications: WB, ELISA
Host: Mouse Monoclonal
BMX Antibody (1C6)
BMX Antibody (1C6)
NBP1-47489
Species: Hu
Applications: WB, ELISA
Host: Mouse Monoclonal
Lysates
BMX Overexpression Lysate (Na ...
BMX Overexpression Lysate (Native)
NBL1-08010
Applications: WB
BMX Overexpression Lysate (Na ...
BMX Overexpression Lysate (Native)
NBP2-10119
Applications: WB
BMX Overexpression Lysate (Na ...
BMX Overexpression Lysate (Native)
NBP2-04569
Applications: WB
Proteins
BMX Recombinant Protein Antig ...
BMX Recombinant Protein Antigen
NBP1-84778PEP
Species: Hu
Applications: AC
Recombinant Human BMX Protein ...
Recombinant Human BMX Protein
P3842
Species: Hu
Applications: Func, PAGE
BMX Peptide
BMX Peptide
NBP1-45548PEP
Species: Hu
Applications: AC
RNAi
BMX RNAi
BMX RNAi
H00000660-R04
Species: Hu
Applications: RNAi, RNAi SP
BMX RNAi
BMX RNAi
H00000660-R03
Species: Hu
Applications: RNAi, RNAi SP

Description

The Tec family of non-receptor tyrosine kinases is composed of six proteins designated Tec, Emt (also known as Itk or Tsk), Btk (previously known as Atk, BPK or Emb), Bmx, Txk (also known as Rlk) and Dsrc28C. All members of the family contain SH3 and SH2 domains and, with the exception of Txk and Dsrc28C, also contain a pleckstrin homology (PH) and a Tec homology (TH) domain in their amino termini. Four alternatively spliced forms of Tec are found to be expressed broadly in cells of hematopoietic lineage and hepatocytes. The 72 kDa Emt gene product associates with CD28 and becomes activated subsequent to CD28 ligation. Btk is necessary for proper B cell development, and mutations in the gene encoding Btk have been associated with families suffering from X-linked agammaglobulinemia, also referred to as Bruton's disease. The 80 kDa Bmx protein shares a high degree of homology with Btk and seems to be expressed at highest levels in the heart. Txk expression is T cell-specific, while expression of the Drosophila Tec homolog, Dsrc28C, is developmentally regulated.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Product By Gene ID 660
Alternate Names
  • EC 2.7.10
  • EC 2.7.10.2
  • NTK38
  • Epithelial and endothelial tyrosine kinase
  • NTK38 tyrosine kinase
  • Bone marrow tyrosine kinase gene in chromosome X protein
  • Etk/Bmx cytosolic tyrosine kinase
  • PSCTK3
  • ETKcytoplasmic tyrosine-protein kinase BMX
  • PSCTK2
  • BMX non-receptor tyrosine kinase

Research Areas for BMX

Find related products by research area and learn more about each of the different research areas below.

Phospho-Specific
Protein Kinase

PTMs for BMX

Learn more about PTMs related to BMX.

Phosphorylation
Cleavage
Acetylation
Methylation
Dephosphorylation
Ribosylation

Bioinformatics Tool for BMX

Discover related pathways, diseases and genes to BMX. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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