BMP-8b Antibody

Western Blot: BMP-8b Antibody [NB300-698] - Dilution 1:500 in diluObuffer, apparent MW of antibody is 49 kDa

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

BMP-8b Antibody Summary

• Immunogen: Synthetic peptide: LQTLRAGDEGWLVL conjugated to KLH, corresponding to amino acids 184-197 of BMP8.
• Localization: Secreted
• Specificity: BMP8
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: BMP8B
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:2000
  • Western Blot 1:500-1:1000
• Application Notes: Western Blot and ELISA: Detects a band of approximately 45 kDa. Optimal dilutions and concentrations should be determined by the end user.

Reactivity Notes

Not yet tested in other species.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Tris/Glycine buffer, pH 7.4-7.8, HEPES,BSA 0.5%, glycerol 30%.
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for BMP-8b Antibody

• BMP-8
• BMP-8b
• bone morphogenetic protein 8b
• MGC131757
• OP-3

Background

The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bonegrowth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identifiedby an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site.Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development.In addition, the fact that this BMP is closely related to BMP5 and BMP7 has led to speculation of possible boneinductive activity. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: BMP8B
• Entrez:
  • 656(Human)
  • 12164(Mouse)