BMP-8a Antibody - BSA Free

Western Blot: BMP-8a Antibody [NBP2-83952] - WB Suggested Anti-BMP8A Antibody. Titration: 1.0 ug/ml. Positive Control: 293T Whole CellBMP8A is strongly supported by BioGPS gene expression data to be expressed in Human HEK293T cells

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 0.5 mg/ml

BMP-8a Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit BMP-8a Antibody - BSA Free (NBP2-83952) is a polyclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human BMP-8a. Peptide sequence: RPPPGCPQRRLGARERRDVQREILAVLGLPGRPRPRAPPAASRLPASAPL The peptide sequence for this immunogen was taken from within the described region.
• Clonality: Polyclonal
• Host: Rabbit
• Gene: BMP8A
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1.0 ug/ml

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS, 2% Sucrose
• Preservative: 0.09% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Affinity purified

Alternate Names for BMP-8a Antibody - BSA Free

• BMP-8a
• bone morphogenetic protein 8a
• Op2
• Osteogenic Protein 2

Background

Bone morphogenic proteins (BMPs) are members of the TGFbeta superfamily. BMPs are involved in the induction of cartilage and bone formation. In vivo studies have shown that BMP-2 (also designated BMP-2A) and BMP-3 can independently induce cartilage formation. Smad3 association with the TGFbeta receptor complex and Smad1 translocation to the nucleus are observed after the addition of BMP-4 (also designated BMP-2B), suggesting that BMP-4 may play a role in activation of the Smad pathway. BMP-5, BMP-6 and BMP-7 all share high sequence homology with BMP-2, indicating that they each may be able to induce cartilage formation. BMP-8 is thought to be involved in early development, as detectable expression has not been found in adult organs.Two BMP-8 proteins exist, namely BMP-8A and BMP-8B (also designated OP-2), and are encoded by two distinct genes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: BMP8A