BMP-6 Antibody (74219) [DyLight 650]

• Reactivity: Hu
• Applications: WB, B/N, ELISA, ELISA(Cap), ELISA(Det)
• Clone: 74219
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 650

BMP-6 Antibody (74219) [DyLight 650] Summary

• Immunogen: Chinese hamster ovary cell line CHO-derived recombinant human BMP‑6
  Arg296-His428
  Accession # Q4VBA3
• Specificity: Detects human BMP-6 in Western blots. In Western blots, no cross-reactivity with recombinant human (rh) BMP‑2, rhBMP‑4, rhBMP‑5, or rhBMP‑7 is observed.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: BMP6
• Purity: Protein A or G purified from ascites

Applications/Dilutions

• Dilutions:
  • ELISA Capture (Matched Antibody Pair)
  • ELISA Detection (Matched Antibody Pair)
  • ELISA Standard (Matched Pair)
  • Neutralization
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from ascites

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for BMP-6 Antibody (74219) [DyLight 650]

• BMP6
• BMP-6
• bone morphogenetic protein 6
• vegetal related growth factor (TGFB-related)
• vegetal-related (TGFB related) cytokine
• VG-1-R
• VG-1-related protein
• Vg1-related sequence
• VGR
• VGR1
• Vgr-1

Background

The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: BMP6