Recombinant Human BMP-4 Protein

Product Discontinued

Recombinant Human BMP-4 Protein Summary

• Description: A recombinant protein corresponding to 116 amino acids of Human BMP-4
• Preparation Method: >98% SDS-PAGE
• Details of Functionality: Biological Activity: recombinant human BMP-4 is biologically active. The ED50 as determined by dose-dependent induction of alkaline phosphatase activity with C2C12 cells is in the range of 2-12 ug/ml.
  Results: 2-12 ug/ml
• Protein/Peptide Type: Recombinant Protein
• Gene: BMP4
• Purity: >98%, by SDS-PAGE
• Endotoxin Note: <0.1 ng/ug

Applications/Dilutions

• Theoretical MW: 13 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Sterile filtered and powder.
• Concentration: Lyoph
• Purity: >98%, by SDS-PAGE
• Reconstitution Instructions: Reconstitute with sterilized 20 mM acetic acid to a final concentration of 0.1 - 1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4C for 1 week or -20C for future use.

Notes

The purity of this protein is >95% pure by SDS-PAGE

Alternate Names for Recombinant Human BMP-4 Protein

• BMP2B
• BMP-2B
• BMP2B1
• BMP2BMCOPS6
• BMP4
• BMP-4
• Bone morphogenetic protein 2B
• bone morphogenetic protein 4
• DVR4
• MCOPS6
• OFC11
• ZYME

Background

BMPs (bone morphogenetic proteins) belong to the TGF-Beta superfamily of structurally related signaling proteins. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. Recombinant human BMP-4 produced from E. coli is a 13 kDa monomeric, non-glycosylated, polypeptide chain containing 116 amino acid residues.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: BMP4