Human BMP-3 ELISA Kit (Colorimetric)

ELISA: Human BMP-3 ELISA Kit (Colorimetric) [NBP2-69993] - Samples were spiked with high concentrations of Human BMP-3 and diluted with Reference Standard & Sample Diluent to produce samples with values within the range of the assay.

ELISA: Human BMP-3 ELISA Kit (Colorimetric) [NBP2-69993] - Standard Curve Reference

• Reactivity: Hu
• Applications: ELISA
• Suitable Sample Type: Serum, plasma and other biological fluids
• Standard Curve Range: 0.16 - 10 ng/mL
• Sensitivity: 0.10 ng/mL

Human BMP-3 ELISA Kit (Colorimetric) Summary

• Specificity: This kit recognizes Human BMP-3 in samples. No significant cross-reactivity or interference between Human BMP-3 and analogues was observed.
• Standard Curve Range: 0.16 - 10 ng/mL
• Sensitivity: 0.10 ng/mL
• Assay Type: Sandwich-ELISA
• Inter-Assay: CV% < 6.07%
• Intra-Assay: CV% < 4.48%
• Spike Recovery: 89-108%
• Sample Volume: 100 uL
• Kit Type: ELISA Kit (Colorimetric)
• Gene: BMP3

Applications/Dilutions

• Dilutions:
  • ELISA

Packaging, Storage & Formulations

• Storage: Storage of components varies. See protocol for specific instructions.

Alternate Names for Human BMP-3 ELISA Kit (Colorimetric)

• BMP3
• BMP-3
• BMP3A
• BMP-3A
• bone morphogenetic protein 3 (osteogenic)
• bone morphogenetic protein 3
• Bone morphogenetic protein 3A
• bone morphogenetic protein-3
• Osteogenin

Background

Bone morphogenetic protein 3 (BMP3) is a 472 amino acid member of the bone morphogenetic protein (BMP) family. BMP3 negatively regulates bone density and is a member of the TGF beta superfamily. It is highly expressed in fracture tissue, predominantly in osteoblasts, osteoclasts and chondroblasts. It may play a role in otosclerosis, osteosarcoma, osteogenesis imperfecta, osteomalacia and periodontitis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

Publications for BMP-3 ELISA Kit (NBP2-69993)(2)

Publications using NBP2-69993

• Venkatesan JK, Schmitt G, Speicher-Mentges S et al. Effects of rAAV-mediated overexpression of bone morphogenetic protein 3 (BMP-3) on the chondrogenic fate of human bone marrow-derived mesenchymal stromal cells Human gene therapy 2022-06-18 [PMID: 35722904] (ELISA)
• Shiwei Xie, Chenyang Zhao, Wei Chen, Gengwu Li, Zhiwei Xiong, Xiangjun Tang, Fan Zhang, Heng Xiao Recombinant human bone morphogenetic protein 2 and 7 inhibit the degeneration of intervertebral discs by blocking the Puma-dependent apoptotic signaling International Journal of Biological Sciences 2021-01-01 [PMID: 34239363]

Bioinformatics

• Gene Symbol: BMP3