BMP-3 Antibody [DyLight 650]

• Reactivity: Hu
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Goat
• Conjugate: DyLight 650

BMP-3 Antibody [DyLight 650] Summary

• Immunogen: E. coli-derived recombinant human BMP‑3
  Ser346-Arg472
  Accession # P12645
• Specificity: Detects human BMP-3 in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross-reactivity with recombinant human (rh) BMP‑2, rhBMP-4, rhBMP-5, rhBMP-6, and rhBMP-7 is observed. This antibody very weakly recognizes native dimeric BMP-3.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: BMP3
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for BMP-3 Antibody [DyLight 650]

• BMP3
• BMP-3
• BMP3A
• BMP-3A
• bone morphogenetic protein 3 (osteogenic)
• bone morphogenetic protein 3
• Bone morphogenetic protein 3A
• bone morphogenetic protein-3
• Osteogenin

Background

Bone morphogenetic protein 3 (BMP3) is a 472 amino acid member of the bone morphogenetic protein (BMP) family. BMP3 negatively regulates bone density and is a member of the TGF beta superfamily. It is highly expressed in fracture tissue, predominantly in osteoblasts, osteoclasts and chondroblasts. It may play a role in otosclerosis, osteosarcoma, osteogenesis imperfecta, osteomalacia and periodontitis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: BMP3