BMP-10 Antibody (654319) [Alexa Fluor® 532]

• Reactivity: Mu
• Applications: IHC
• Clone: 654319
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Alexa Fluor 532

BMP-10 Antibody (654319) [Alexa Fluor® 532] Summary

• Immunogen: Chinese hamster ovary cell line CHO-derived recombinant human BMP-10
  Asn314-Arg421
  Accession # Q9R229
• Specificity: Detects mouse BMP-10 in direct ELISAs. In direct ELISAs, 100% cross-reactivity with recombinant human (rh) BMP-10 and less than 10% cross‑reactivity with rhBMP-8a and recombinant mouse (rm) BMP‑8b is observed. No cross-reactivity with rmBMP-3, -4, -5
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for BMP-10 Antibody (654319) [Alexa Fluor® 532]

• BMP10
• BMP-10
• bone morphogenetic protein 10
• MGC126783

Background

Bone morphogenetic protein 10 (BMP-10) is a TGF-beta superfamily member whose expression is restricted to the developing and postnatal heart. It is synthesized as a 424 amino acid (aa) pre-proprotein with a putative 21 aa signal peptide, a 292 aa propeptide, and a 108 aa mature protein. Mature BMP-10 is secreted as a 25 kDa disulfide-linked homodimer. The mouse BMP-10 proprotein shares 86% and 95% aa sequence identity with human and rat BMP-10, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.