BMP-1/PCP Antibody [mFluor Violet 450 SE]

• Reactivity: Hu
• Applications: WB, IP
• Clonality: Polyclonal
• Host: Goat
• Conjugate: mFluor Violet 450 SE

BMP-1/PCP Antibody [mFluor Violet 450 SE] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human BMP‑1/PCP
  Ala121-Gln730
  Accession # NP_001190
• Specificity: Detects human BMP‑1/PCP direct ELISAs and Western blots. In direct ELISAs, approximately 10% cross-reactivity with recombinant human (rh) TLL-2 is observed, and less than 1% cross-reactivity with rhBMP-2, -3, -3b, -4, -5, -6, -7, -8, -9, -10, and -15 is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: BMP1
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for BMP-1/PCP Antibody [mFluor Violet 450 SE]

• BMP1
• BMP-1
• bone morphogenetic protein 1
• EC 3.4.24
• EC 3.4.24.19
• FLJ44432
• Mammalian tolloid protein
• mTld
• PCOLC
• PCP
• PCP2
• procollagen C-endopeptidase
• Procollagen C-proteinase
• TLD

Background

Bone morphogenetic protein 1 (BMP1) is a 986 amino acid member of the bone morphogenetic protein (BMP) family. It was initially discovered for its role to induce cartilage and bone formation. It is a metalloprotease that cleaves the C-terminus of procollagen I, II and III while other BMPs are part of the TGF beta superfamily. It may play a role in herniation, congestive heart failure, breast cancer, myelofibrosis with myeloid metaplasia and infection by HIV-1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: BMP1