BMP-1/PCP Products

Description

BMP1 encodes a Metallopeptidase M12A type protease that is comprised of an amino terminal signal peptide, prodomain and an astacin-like protease domain followed by CUB and EGF-like motifs. BMP1 protein has been shown to cleave chordin, the C-terminal propeptides of procollagen I, II, III and VII, pro-lysyl oxidase, probiglycan, and laminin-5, and its expression has been shown to induce cartilage and bone formation in vivo. At least six spliced variants have been reported. These share the N-terminal protease domain but differ in the C-terminus, and thus contain varying numbers of CUB and EGF-like domains.

Bioinformatics

Entrez	649 Human
Uniprot	P13497 Human
Product By Gene ID	649
Alternate Names	BMP1 BMP-1 bone morphogenetic protein 1 EC 3.4.24 EC 3.4.24.19 FLJ44432 Mammalian tolloid protein mTld PCOLC PCP PCP2 procollagen C-endopeptidase Procollagen C-proteinase TLD

Research Areas for BMP-1/PCP

Find related products by research area and learn more about each of the different research areas below.

Cytokine Research