Betacellulin/BTC Antibody (34362) [FITC]

• Reactivity: Hu
• Applications: ELISA, ELISA(Cap), ELISA(Det)
• Clone: 34362
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: FITC

Betacellulin/BTC Antibody (34362) [FITC] Summary

• Immunogen: E. coli-derived recombinant human Betacellulin
  Asp32-Tyr111
  Accession # P35070
• Specificity: Detects human Betacellulin in ELISAs and Western blots. In Western blots, this antibody does not cross-react with recombinant human (rh) EGF, rhHB‑EGF, rhTGF‑ alpha , rhHRG‑ alpha , or rhAR under non-reducing conditions.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: BTC
• Purity: Protein A or G purified from ascites

Applications/Dilutions

• Dilutions:
  • ELISA Capture (Matched Antibody Pair)
  • ELISA Detection (Matched Antibody Pair)
  • ELISA Standard (Matched Pair)
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from ascites

Alternate Names for Betacellulin/BTC Antibody (34362) [FITC]

• Betacellulin
• BTC
• probetacellulin

Background

Betacellulin (BTC) is a member of the EGF (epidermal growth factor) family. The transmembrane BTC precursor undergoes proteolytic cleavage, releasing the BTC ligand. It binds to both EGFR/ErbB-1 and ErbB-4 receptor tyrosine kinases. Betacellulin has been found to affect influence various cell types, such as neural stem cells (NSCs), mesenchymal stem cells (MSCs), pancreatic beta cells, retinal pigment epithelial cells and smooth muscle cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: BTC