BCL11B Antibody (CL6426) - Azide and BSA Free

Analysis in human tonsil and pancreas tissues using NBP3-44407 antibody. Corresponding BCL11B RNA-seq data are presented for the same tissues.

Staining of human skin shows moderate to strong nuclear positivity in dermal cells.

Staining of human pancreas shows no positivity in exocrine glandular cells as expected.

Staining of mouse cerebral cortex shows moderate to strong nuclear positivity in neurons, mainly in layers 5-6.

Analysis in mouse cerebral cortex tissue.

Staining of mouse hippocampus shows strong nuclear positivity in neurons in the granular cell layer of dentate gyrus.

Staining of mouse hippocampus shows strong nuclear positivity in neurons in CA1 pyramidal layer.

Analysis in human cerebral cortex tissue.

Staining of human tonsil shows moderate to strong nuclear positivity, mainly in non - germinal center cells.

• Reactivity: Hu, Mu
• Applications: WB, IHC
• Clone: CL6426
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free
• Concentration: LYOPH

BCL11B Antibody (CL6426) - Azide and BSA Free Summary

• Description: Novus Biologicals Mouse BCL11B Antibody (CL6426) - Azide and BSA Free (NBP2-76493) is a monoclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was generated using a synthetic peptide of Q9C0K0, with the exact immunogen sequence remaining proprietary.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: BCL11B
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry-Paraffin 1:500 - 1:1000
  • Western Blot 1 ug/ml
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Lyophilized from a 0.2 um filtered solution in PBS with Trehalose
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Protein A purified
• Reconstitution Instructions: Centrifuge the vial of lyophilized antibody at 12,000 x g for 20 seconds. Reconstitute by adding sterile, distilled water to achieve a final antibody concentration of 1mg/ml.

Alternate Names for BCL11B Antibody (CL6426) - Azide and BSA Free

• B-cell CLL/lymphoma 11B (zinc finger protein)
• B-cell CLL/lymphoma 11B
• B-cell CLL/lymphoma 11B/T-cell receptor delta constant region fusion protein
• B-cell lymphoma/leukaemia 11B
• B-cell lymphoma/leukemia 11B
• BCL-11B
• BCL11B/TRDC fusion
• COUP-TF-interacting protein 2
• CTIP-2
• CTIP2ZNF856B
• hRit1
• hRIT1-alpha
• Radiation-induced tumor suppressor gene 1 protein
• RIT1
• zinc finger protein hRit1 alpha

Background

The BCL11B gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. The specific function of this gene has not yet been determined. Two alternatively spliced transcript

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: BCL11B