Less than 1 EU/ug of rHuBcl-w as determined by LAL method.
18.6 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Read Publication using NBP2-34895 in the following applications:
0.2 um filtered concentrated solution in 25 mM Hepes, pH 7.4, 100 mM KCl, 10 % Glycerol, 5 % Trehalose, 0.02 % Tween-80.
>95%, by SDS-PAGE and HPLC
This product is stable for 6 months from date of receipt at -20 to -70 degrees C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Stock solutions should be aliquoted and stored at < -20 degrees C. Further dilutions should be made in appropriate buffered solutions
Alternate Names for Recombinant Human BCL-W/BCL2L2 Protein
Apoptosis regulator Bcl-W
BCLWbcl-2-like protein 2
BCL2L2, also named as Bcl-w, belongs to the Bcl-2 family and is encoded by the BCL2L2 gene in human. BCL2L2 (Bcl-w) is expressed in a wide range of tissues with highest levels in brain, spinal cord, testis, pancreas, heart, spleen and mammary glands, and moderate levels in thymus, ovary and small intestine. It is also expressed in cell lines of myeloid, fibroblast and epithelial origin. BCL2L2 (Bcl-w) is an anti-apoptotic (pro-survival) protein that reduces cell apoptosis under cytotoxic conditions. Mature human BCL2L2 (Bcl-w) shares 98 % - 99 % amino acid sequence identity with murine, bovine, canine Bcl-w.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.
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PRODUCT AVAILABILITY: Update Regarding the Evolving COVID-19 Situation
Bio-Techne appreciates the critical role that you and our products and services play in research efforts to further scientific innovation and discovery. We are continually assessing our manufacturing and supplier capabilities during the COVID-19 situation and are implementing precautionary measures to ensure uninterrupted supply of products and services. Currently, and as we abide by local shelter in place orders across the world, we are fully operational and do not anticipate any material supply disruptions across our Bio-Techne brands and product lines. As the situation evolves, our goal is to utilize preventive measures to reduce the threat that COVID-19 poses to our ability to meet the needs of our customers globally.