Recombinant Human BCL-W/BCL2L2 Protein

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SDS-Page: Human BCL-W/BCL2L2 Protein [NBP2-34895]

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Func, PAGE
Format
Carrier-Free

Order Details

Recombinant Human BCL-W/BCL2L2 Protein Summary

Description
A single, non-glycosylated polypeptide chain corresponding to 171 residues of BCL-W/BCL2L2.

Source: Escherichia coli

Amino Acid Sequence: ATPASAPDTR ALVADFVGYK LRQKGYVCGA GPGEGPAADP LHQAMRAAGD EFETRFRRTF SDLAAQLHVT PGSAQQRFTQ VSDELFQGGP NWGRLVAFFV FGAALCAESV NKEMEPLVGQ VQEWMVAYLE TQLADWIHSS GGWAEFTALY GDGALEEARR LREGNWASVR T

Details of Functionality
Test in Process.
Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
BCL2L2
Purity
>95%, by SDS-PAGE and HPLC
Endotoxin Note
Less than 1 EU/ug of rHuBcl-w as determined by LAL method.

Applications/Dilutions

Theoretical MW
18.6 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Publications
Read Publication using
NBP2-34895 in the following applications:

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
0.2 um filtered concentrated solution in 25 mM Hepes, pH 7.4, 100 mM KCl, 10 % Glycerol, 5 % Trehalose, 0.02 % Tween-80.
Preservative
5% Trehalose
Purity
>95%, by SDS-PAGE and HPLC

Notes

This product is stable for 6 months from date of receipt at -20 to -70 degrees C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Stock solutions should be aliquoted and stored at < -20 degrees C. Further dilutions should be made in appropriate buffered solutions

Alternate Names for Recombinant Human BCL-W/BCL2L2 Protein

  • Apoptosis regulator Bcl-W
  • BCL2L2
  • Bcl2-L-2
  • BCL2-like 2
  • Bclw
  • Bcl-w
  • BCLWbcl-2-like protein 2
  • KIAA0271BCL2-L-2

Background

BCL2L2, also named as Bcl-w, belongs to the Bcl-2 family and is encoded by the BCL2L2 gene in human. BCL2L2 (Bcl-w) is expressed in a wide range of tissues with highest levels in brain, spinal cord, testis, pancreas, heart, spleen and mammary glands, and moderate levels in thymus, ovary and small intestine. It is also expressed in cell lines of myeloid, fibroblast and epithelial origin. BCL2L2 (Bcl-w) is an anti-apoptotic (pro-survival) protein that reduces cell apoptosis under cytotoxic conditions. Mature human BCL2L2 (Bcl-w) shares 98 % - 99 % amino acid sequence identity with murine, bovine, canine Bcl-w.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Publications for BCL-W/BCL2L2 Recombinant Protein (NBP2-34895)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: Ctrl.


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Bioinformatics

Gene Symbol BCL2L2
Uniprot