BAF180/PB1 Products

Antibodies
BAF180/PB1 Antibody
BAF180/PB1 Antibody
NB100-79833
Species: Hu, Guinea Pig, Primate, Mouse, Rabbit, Rat, Chinese Hamster, Rhesus Macaque
Applications: WB, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Polyclonal
BAF180/PB1 Antibody (CL0331)
BAF180/PB1 Antibody (CL0331)
NBP2-30673
Species: Hu, Mouse, Rat
Applications: WB, IHC
Host: Mouse Monoclonal
BAF180/PB1 Antibody
BAF180/PB1 Antibody
NBP1-90016
Species: Hu, Mu, Rt, Mouse, Rat
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
BAF180/PB1 Overexpression Lys ...
BAF180/PB1 Overexpression Lysate (...
H00055193-T01
Species: Hu
Applications: WB
BAF180/PB1 Overexpression Lys ...
BAF180/PB1 Overexpression Lysate (...
H00055193-T02
Species: Hu
Applications: WB
Proteins
BAF180/PB1 Recombinant Protei ...
BAF180/PB1 Recombinant Protein
H00055193-P01
Species: Hu
Applications: WB, ELISA, PA
BAF180/PB1 Recombinant Protei ...
BAF180/PB1 Recombinant Protein Ant...
NBP1-90016PEP
Species: Hu
Applications: AC
RNAi
BAF180/PB1 RNAi
BAF180/PB1 RNAi
H00055193-R04
Species: Hu
BAF180/PB1 RNAi
BAF180/PB1 RNAi
H00055193-R03
Species: Hu
BAF180/PB1 RNAi
BAF180/PB1 RNAi
H00055193-R01
Species: Hu

Description

The SMARCs (SWI/SNF-related, matrix-associated, actin-dependent regulators of chromatin), and BAFs (BRG1-associated factors), have been identified as components of the mammalian SWI/SNF-like chromatin-remodeling protein complexes. These multi-protein complexes are proposed to function as ATP-driven motors that translocate along DNA and destabilize nucleosomal structures to facilitate transcription factor binding. PB1/BAF180 is a component of the SWI/SNF-B (PBAF) complex. It contains six bromodomains which are defined by a 110 amino-acid module that interacts with acetylated lysine and is found in many chromatin binding proteins and histone acetyltransferases. PB1/BAF180 has been proposed to function as a tumor suppressor protein. Recently, PB1/BAF180 has been found to play a role in mediating cell cycle arrest in response to DNA damage via the regulation of the tumor suppressor p21. Alternate names for PB1/BAF180 include protein polybromo-1, polybromo-1D, BRG1-associated factor 180, hPB1, and PBRM1.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 55193
Alternate Names
  • Polybromo-1D
  • MGC156156
  • protein polybromo-1
  • MGC156155
  • polybromo-1D
  • hPB1
  • BAF180PB1BRG1-associated factor 180
  • polybromo 1

PTMs for BAF180/PB1

Learn more about PTMs related to BAF180/PB1.

Acetylation
Methylation
Ubiquitination

Bioinformatics Tool for BAF180/PB1

Discover related pathways, diseases and genes to BAF180/PB1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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