B7-H6 Antibody (875023) - Azide and BSA Free

Flow Cytometry: B7-H6 Antibody (875023) - Azide Free [MAB71441] - A cell surface stain was performed on Ramos cells with B7-H6 Antibody (875023) MAB71441PE (blue) and a matched isotype control (orange). Cells were incubated in an antibody dilution of 2.5 ug/mL for 20 minutes at room temperature. Both antibodies were conjugated to Phycoerythin.

Flow (Intracellular): B7-H6 Antibody (875023) - Azide Free [MAB71441] - A cell surface stain was performed on U-937 cells with B7-H6 Antibody (875023) MAB71441AF647 (blue) and a matched isotype control(orange). Cells were incubated in an antibody dilution of 2.5 ug/mL for 20 minutes at room temperature. Both antibodies were conjugated to Alexa Fluor 647.

• Reactivity: Hu
• Applications: Flow, CyTOF-ready
• Clone: 875023
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free
• Concentration: 1.0 mg/ml

B7-H6 Antibody (875023) - Azide and BSA Free Summary

• Immunogen: Partial recombinant human B7-H6 protein (amino acids1-262). [UniProt Q68D85]
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: NCR3LG1
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow (Intracellular)
  • Flow Cytometry
• Application Notes: This antibody is Cytof ready.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: No Preservative
• Concentration: 1.0 mg/ml
• Purity: Protein A or G purified

Alternate Names for B7-H6 Antibody (875023) - Azide and BSA Free

• B7 homolog 6
• B7H6
• B7-H6
• DKFZp686I21167
• DKFZp686O24166
• NCR3LG1

Background

B7-H6 is a transmembrane immune regulatory protein that binds to NKp30 expressed on NK cells. Ligation of NKp30 by B7-H6 induces NK cell activation and target cell cytolysis. B7-H6 is expressed on a wide range of hematopoietic, carcinoma, and melanoma tumor cells. The expression of NKp30 ligands on tumor cells correlates with tumor cell sensitivity to NKp30-dependent cell lysis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: NCR3LG1