ATRX Antibody

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Western Blot: ATRX Antibody [NBP1-32851] - Various whole cell extracts (30 ug) were separated by 5% SDS-PAGE, and the membrane was blotted with ATRX antibody [C3], C-term diluted at 1:1000. The HRP-conjugated ...read more
Immunocytochemistry/ Immunofluorescence: ATRX Antibody [NBP1-32851] - Paraformaldehyde-fixed HeLa, using antibody at 1:200 dilution.
Immunohistochemistry-Paraffin: ATRX Antibody [NBP1-32851] - human breast carcinoma dilution: 1:500.
Western Blot: ATRX Antibody [NBP1-32851] - Whole cell extracts (30 ug) was separated by 5% SDS-PAGE, and the membrane was blotted with ATRX antibody diluted by 1:1000.
Western Blot: ATRX Antibody [NBP1-32851] - Various whole cell extracts (30 ug) were separated by 5% SDS-PAGE, and the membrane was blotted with ATRX antibody diluted at a dilution of 1:1000.
Western Blot: ATRX Antibody [NBP1-32851] - Non-transfected (-) and transfected (+) 293T whole cell extracts (30 ug) were separated by 5% SDS-PAGE, and the membrane was blotted with ATRX antibody [C3], C-term.
Immunohistochemistry-Paraffin: ATRX Antibody [NBP1-32851] - Human endometrial carcinoma dilution: 1:500.
Immunohistochemistry-Paraffin: ATRX Antibody [NBP1-32851] - Human lung carcinoma dilution: 1:500
Immunoprecipitation: ATRX Antibody [NBP1-32851] - Immunoprecipitation of ATRX protein from 293T whole cell extracts using 5 ug of ATRX antibody [C3], C-term (NBP1-32851). Western blot analysis was performed using ATRX ...read more

Product Details

Summary
Reactivity Hu, Mu, Rt, PmSpecies Glossary
Applications WB, ICC/IF, IHC, IHC-P, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.16 mg/ml
     

Genetic Strategies

   

Order Details

ATRX Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the C-terminus region of human ATRX. The exact sequence is proprietary.
Localization
Nucleus
Predicted Species
Primate (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ATRX
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
  • Immunocytochemistry/Immunofluorescence 1:100-1:1000
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
  • Immunoprecipitation 1:100-1:500
Theoretical MW
283 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Publications
Read Publications using
NBP1-32851 in the following applications:

  • WB
    2 publications

Reactivity Notes

Chimpanzee (100%).

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.0) and 20% Glycerol
Preservative
0.025% Proclin 300
Concentration
1.16 mg/ml
Purity
Immunogen affinity purified

Alternate Names for ATRX Antibody

  • alpha thalassemia/mental retardation syndrome X-linked (RAD54 (S. cerevisiae)homolog)
  • alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S.cerevisiae)
  • alpha thalassemia/mental retardation syndrome X-linked
  • ATP-dependent helicase ATRX
  • ATR2
  • DNA dependent ATPase and helicase
  • EC 3.6.1
  • EC 3.6.4.12
  • helicase 2, X-linked
  • Juberg-Marsidi syndrome
  • MGC2094
  • MRXHF1
  • RAD54 homolog
  • RAD54L
  • SFM1
  • SHS
  • transcriptional regulator ATRX
  • XH2RAD54
  • X-linked helicase II
  • X-linked nuclear protein
  • XNPZNF-HX
  • Zinc finger helicase
  • Znf-HX

Background

The protein encoded by this gene contains an ATPase/helicase domain, and thus it belongs to the SWI/SNF family of chromatin remodeling proteins. The mutations of this gene are associated with an X-linked mental retardation (XLMR) syndrome most often accompanied by alpha-thalassemia (ATRX) syndrome. These mutations have been shown to cause diverse changes in the pattern of DNA methylation, which may provide a link between chromatin remodeling, DNA methylation, and gene expression in developmental processes. This protein is found to undergo cell cycle-dependent phosphorylation, which regulates its nuclear matrix and chromatin association, and suggests its involvement in the gene regulation at interphase and chromosomal segregation in mitosis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for ATRX Antibody (NBP1-32851)(2)

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: WB.


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WB
(2)
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Mouse
(1)
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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Bioinformatics

Gene Symbol ATRX
Entrez
Uniprot