ATIC Antibody (OTI1D2) [Janelia Fluor® 646]

• Reactivity: Hu, Mu, Rt, Ca, Pm
• Applications: WB, Flow
• Clone: OTI1D2
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Janelia Fluor 646

ATIC Antibody (OTI1D2) [Janelia Fluor® 646] Summary

• Immunogen: Full length recombinant protein of human ATIC (NP_004035) produced in HEK293T cells.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: ATIC
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for ATIC Antibody (OTI1D2) [Janelia Fluor® 646]

• 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMPcyclohydrolase
• 5-aminoimidazole-4-carboxamide-1-beta-D-ribonucleotidetransformylase/inosinicase
• AICAR formyltransferase/IMP cyclohydrolase bifunctional enzyme
• AICAR
• AICARFT
• AICARFT/IMPCHASE
• bifunctional purine biosynthesis protein PURH
• IMPCHASE
• phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
• PURHFLJ93545

Background

ATIC is a 5 aminoimidazole 4 carboxamide ribonucleotide formyltransferase which helps catalyze the penultimate and final steps of the de novo purine biosynthetic pathway. The human ATIC cDNA encodes a deduced 591 amino acid protein that is 81% identical to the chicken sequence.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ATIC