ATAD3A Antibody - BSA Free

Western Blot: ATAD3A Antibody [NBP1-76586] - Daudi cell lysate with ATAD3A antibody at 1 ug/mL .

Immunocytochemistry/Immunofluorescence: ATAD3A Antibody [NBP1-76586] - Immunocytochemistry of ATAD3A in Daudi cells with ATAD3A antibody at 20 ug/mL.

Immunocytochemistry/ Immunofluorescence: ATAD3A Antibody - BSA Free [NBP1-76586] - Immunofluorescence of ATAD3A in Daudi cells with ATAD3A antibody at 20 ug/mL.

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

ATAD3A Antibody - BSA Free Summary

• Immunogen: Antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human ATAD3A. The immunogen is located within amino acids 110 - 160 of ATAD3A. Amino Acid Squence: AVQTQERLSGSASPEQVPA
• Specificity: ATAD3A antibody is predicted to not cross-react with other ATAD protein family members. At least two isoforms are known to exist.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ATAD3A
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence 20 ug/ml
  • Western Blot 1 ug/ml
• Control Peptide:

  ATAD3A Peptide (NBP1-76586PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for ATAD3A Antibody - BSA Free

• ATPase family AAA domain-containing protein 3A
• ATPase family, AAA domain containing 3A
• FLJ10709
• FLJ35514

Background

ATAD3A is a member of the AAA ATPase family, a family of proteins that catalyze ATP into ADP and are involved in several cellular functions such as cell-cycle regulation, protein proteolysis and transport. The AAA ATPase family is characterized by a highly conserved AAA motif containing Walker homology sequences and imparting ATPase activity. Mitochondrial membrane proteins ATAD3A/B contribute to the stabilization of nucleoids and may participate in the transformation pathway and the chemosensitivity of oligodendrogliomas. The gene encoding ATAD3A/B/C maps to human chromosome 1 and has been suggested to be an anti-apoptotic marker.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for ATAD3A Antibody (NBP1-76586)(2)

Publications using NBP1-76586

• Li Q, Chu Y, Li S et al. The oncoprotein MUC1 facilitates breast cancer progression by promoting Pink1-dependent mitophagy via ATAD3A destabilization Cell death & disease 2022-10-26 [PMID: 36289190]
• Igelmann S, Lessard F, Uchenunu O et al. A hydride transfer complex reprograms NAD metabolism and bypasses senescence Molecular cell 2021-09-16 [PMID: 34547241]

Bioinformatics

• Gene Symbol: ATAD3A
• Uniprot:
  • Q9NVI7(Human)