ASGPR1 Antibody (950203) [Janelia Fluor® 635]

Product Discontinued

ASGPR1 Antibody (950203) [Janelia Fluor® 635] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human ASGR1/ASGPR1
  Gln62-Leu291
  Accession # P07306
• Specificity: Detects human ASGR1/ASGPR1 in direct ELISAs.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry
  • Immunohistochemistry
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for ASGPR1 Antibody (950203) [Janelia Fluor® 635]

• ASGPR 1
• ASGP-R 1
• ASGPR
• ASGPR1
• ASGR1
• asialoglycoprotein receptor 1
• CLEC4H1
• CLEC4H1ASGPR1
• C-type lectin domain family 4 member H1
• Hepatic lectin H1
• HL-1
• MHL1
• RHL1

Background

Partially deglycosylated plasma glycoproteins and immunoglobulin IgA2 allotypes are efficiently and specificallyremoved from circulation by a receptor-mediated process. The asialoglycoprotein receptor binds to desialylated(galactosyl-terminal) glycoproteins. It transports these glycoproteins via a series of membrane vesicles and tubulesto an acidic-sorting organelle where the receptor and ligand dissociate. Then the receptor is recycled back to thecell surface and the ligand is transported to the lysosomes for degradation. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.