ASCL1/Mash1 Antibody [DyLight 405]

• Reactivity: Mu
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Goat
• Conjugate: DyLight 405

ASCL1/Mash1 Antibody [DyLight 405] Summary

• Immunogen: E. coli-derived recombinant mouse ASCL1/Mash1
  His74-Asp173 (Gln160Glu)
  Accession # Q53WV9
• Specificity: Detects mouse ASCL1/Mash1 in direct ELISAs and Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: ASCL1
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for ASCL1/Mash1 Antibody [DyLight 405]

• achaete-scute complex (Drosophila) homolog-like 1
• achaete-scute complex homolog 1 (Drosophila)
• achaete-scute complex-like 1 (Drosophila)
• achaete-scute homolog 1
• ASCL1
• ASH1
• ASH-1
• ASH1MASH1
• BHLHA46
• bHLHa46achaete-scute complex-like 1
• Class A basic helix-loop-helix protein 46
• HASH1
• HASH1achaete scute protein
• Mash1

Background

MASH1 encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ASCL1