Arylsulfatase B/ARSB Antibody [Alexa Fluor® 700]

• Reactivity: Hu
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: Alexa Fluor 700

Arylsulfatase B/ARSB Antibody [Alexa Fluor® 700] Summary

• Immunogen: Chinese hamster ovary cell line CHO-derived recombinant human Arylsulfatase B/ARSB
  Ser37-Met533 (Val376Met)
  Accession # P15848
• Specificity: Detects human Arylsulfatase B/ARSB in Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Arylsulfatase B/ARSB Antibody [Alexa Fluor® 700]

• ARSB
• Arylsulfatase B
• ASB
• EC 3.1.6.12
• G4S
• MPS6
• N-acetylgalactosamine-4-sulfatase

Background

ARSB, also known as N-acetylgalactosamine-4-sulfatase, is a lysosomal glycoprotein and one of at least nine human arylsulfatases that catalyze the hydrolysis of sulfate ester bonds. ARSB deficiency is causative of the lysosomal storage disease Mucopolysaccharidosis VI. Human ARSB is cleaved intracellularly into fragments which remain associated with a disulfide linkage. Mature human ARSB (aa 37-533) shares 80% amino acid sequence identity with mouse and rat ARSB.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.