ART2.2/Art2b Antibody (Nika102) [DyLight 488]

• Reactivity: Mu
• Applications: Flow, IP
• Clone: Nika102
• Clonality: Monoclonal
• Host: Rat
• Conjugate: DyLight 488

ART2.2/Art2b Antibody (Nika102) [DyLight 488] Summary

• Description: This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
  
  For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
• Immunogen: pME.CD8LF-ART2.2
• Localization: Cell Membrane; lipid anchor; GPI anchor (By similarity).
• Specificity: NB100-65853 recognizes the gene product of the mouse ADP-ribosyltransferase (ART) 2.2 gene, an ortholog of rat RT6. ART2.2 expressed exclusively by mature T-cells. Levels of ART2.2 expression vary between inbred strains of mice and is absent in NZW mice, in which the ART2.2 gene is deleted (PMID: 10570289, Koch-Nolte et al. 1999).
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat
• Gene: Art2b
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Immunoprecipitation
• Application Notes: Recommended applications are based on validated applications from the unconjugated base product NB100-65853. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein G purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for ART2.2/Art2b Antibody (Nika102) [DyLight 488]

• ADP-ribosyltransferase 2b
• Rt6
• Rt-6
• Rt6.2
• Rt6-2

Background

The mouse ADP ribosyltransferase (ART) 2.2 gene is ortholog of rat RT6, and is expressed exclusively by mature T cells. Levels of ART2.2/Art2b expression vary between inbred strains of mice and is absent in NZW mice, in which the ART2.2/Art2b gene is deleted. ART2.2/Art2b has both NAD(+) glycohydrolase and ADP ribosyltransferase activity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: Art2b
• Entrez:
  • 11872(Mouse)
• Uniprot:
  • O35975(Mouse)