Aromatase Antibody (H4) - BSA Free

Product Discontinued

Aromatase Antibody (H4) - BSA Free Summary

• Immunogen: Synthetic peptide corresponding to AAs 376-390 of human aromatase (KALEDDVIGYPVKK)
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: CYP19A1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:100
  • Immunohistochemistry 1:50 - 1:100
  • Western Blot 1:50-1:5000
• Application Notes: Positive control(s): Placenta
• Theoretical MW: 55 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Marmoset

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein A purified

Alternate Names for Aromatase Antibody (H4) - BSA Free

• ARO1
• ARO1EC 1.14.14.1
• Aromatase
• AROsubfamily XIX (aromatization of androgens)
• CYAR
• CYARMGC104309
• CYP19
• CYP19A1
• CYPXIX
• cytochrome P450, family 19, subfamily A, polypeptide 1
• Cytochrome P-450AROM
• EC 1.14.14.14
• Estrogen synthase
• microsomal monooxygenase

Background

CYP450 Aromatase is part of the CYP19A1 family involved in the aromatization of androgens to estrogens, a highly conserved mechanism amongst mammals. Clone H4 recognizes a conserved epitope on the CYP450 aromatase, allowing for detection of aromatase levels using various analysis methods.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Aromatase Antibody (NBP2-61939)(1)

Publication using NBP2-61939

• Miyazaki Y, Orisaka M, Fujita Y et al. Steroidogenic differentiation of human amniotic membrane-derived mesenchymal stem cells into a progesterone-/androgen-producing cell lineage by SF-1 and an estrogen-producing cell lineage by WT1−KTS Frontiers in Endocrinology 2024-09-18 [PMID: 39359415]

Bioinformatics

• Gene Symbol: CYP19A1