ARNT2 Antibody - BSA Free

Western Blot: ARNT2 Antibody - BSA Free [NBP3-47949] - HEK-293 cells were subjected to SDS PAGE followed by western blot with (ARNT2 antibody) at dilution of 1:1000

Immunohistochemistry: ARNT2 Antibody - BSA Free [NBP3-47949] - Immunohistochemistry of paraffin-embedded human kidney using (ARNT2 antibody) at dilution of 1:100

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

ARNT2 Antibody - BSA Free Summary

• Immunogen: aryl-hydrocarbon receptor nuclear translocator 2. (Uniprot# Q9HBZ2)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ARNT2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry 1:50 - 1:200
  • Western Blot 1:500 - 1:2000
• Theoretical MW: 79 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS, 50% Glycerol, pH (7.3)
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for ARNT2 Antibody - BSA Free

• ARNT protein 2
• aryl-hydrocarbon receptor nuclear translocator 2
• bHLHe1BHLHE1
• Class E basic helix-loop-helix protein 1
• KIAA0307aryl hydrocarbon receptor nuclear translocator 2

Background

AhR, Arnt 1, Arnt 2 and BMAL1 are members of a family of transcription factors that contain a basic helix-loop-helix motif and a common "PAS" motif. The aromatic (aryl) hydrocarbon receptor, AhR, is a ligand dependent transcription factor that interacts with specific DNA sequences termed xenobiotic responsive elements (XREs) to activate several genes including CYP1A1, glutathione S-transferase Ya subunit and DT-diaphorase. The Ah receptor nuclear translocator proteins (Arnt 1 or Arnt 2) are required for ligand-dependent nuclear translocation of the Ah receptor and are also necessary for Ah receptor binding to the XRE element. BMAL1 (Brain and Muscle Arnt-like protein 1), also designated Arnt 3, TIC, JAP3 or MOP-3, has been shown to dimerize with Clock and bind to the promoter region of mPer1, suggesting that this protein plays a role in regulation of circadian oscillation in mammals.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ARNT2