APLP-2 Antibody

Western Blot: APLP-2 Antibody [NBP1-32814] - Various whole cell extracts (30 ug) were separated by 7.5% SDS-PAGE, and the membrane was blotted with APLP2 antibody [N1N2], N-term diluted at 1:1000.

Immunohistochemistry-Paraffin: APLP-2 Antibody [NBP1-32814] - Mouse fore brain dilution: 1:500. Antigen Retrieval: TrilogyTM (EDTA based) buffer, 15min

Western Blot: APLP-2 Antibody [NBP1-32814] - 50 ug mouse brain lysate/extract 7. 5 % SDS-PAGE gel, antibody dilution 1:1000.

Immunohistochemistry-Paraffin: APLP-2 Antibody [NBP1-32814] - Mouse liver dilution: 1:500. Antigen Retrieval: TrilogyTM (EDTA based) buffer, 15min

• Reactivity: Hu, Mu, Pm
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

APLP-2 Antibody Summary

• Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human APLP-2. The exact sequence is proprietary.
• Localization: Cell membrane, Single-pass type I membrane protein , Nucleus , Cell membrane , Nucleus
• Predicted Species: Chimpanzee (99%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: APLP2
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
  • Western Blot 1:500-1:3000
• Theoretical MW: 87 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Rat (89%), Chicken (83%).

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS, 1% BSA, 20% Glycerol
• Preservative: 0.025% Proclin 300
• Purity: Antigen Affinity-purified

Alternate Names for APLP-2 Antibody

• amyloid beta (A4) precursor-like protein 2
• amyloid precursor protein homolog HSD-2
• Amyloid protein homolog
• amyloid-like protein 2
• APLP2
• APLP-2
• APPH
• APPHCDEI box-binding protein
• APPL2
• CDEBP
• WALPLP2
• YWK-II

Background

APLP2, also known as Amyloid-like protein 2, consists of a 763 amino acid isoform that is 87 kDa, and is involved in hemostasis regulation and neuromuscular transmission regulation. Current research is being conducted on the relationship between APLP2 and several diseases and disorders, such as spinocerebellar ataxia, lissencephaly, cholesterol, pancreatitis, neuroblastoma, infertility, thrombosis, breast cancer, neuronitis, brain disease, dementia, and thrombosis. APLP2 interacts with JUN, APLP1, ZNF512B, DEDD, and ETS1 on homeostasis and behavior pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Publications for APLP-2 Antibody (NBP1-32814)(1)

Publication using NBP1-32814

• Eckfeld C, Schoeps B, H�u�ler D et al. TIMP-1 is a novel ligand of Amyloid Precursor Protein and triggers a proinflammatory phenotype in human monocytes Journal of Cell Biology 2023-02-06 [PMID: 36629908] (Flow Cytometry)

Bioinformatics

• Gene Symbol: APLP2