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APLP2, also known as Amyloid-like protein 2, consists of a 763 amino acid isoform that is 87 kDa, and is involved in hemostasis regulation and neuromuscular transmission regulation. Current research is being conducted on the relationship between APLP2 and several diseases and disorders, such as spinocerebellar ataxia, lissencephaly, cholesterol, pancreatitis, neuroblastoma, infertility, thrombosis, breast cancer, neuronitis, brain disease, dementia, and thrombosis. APLP2 interacts with JUN, APLP1, ZNF512B, DEDD, and ETS1 on homeostasis and behavior pathways.