Annexin A6 Antibody

Western Blot: Annexin A6 Antibody [H00000309-B01P] - Analysis of ANXA6 expression in human kidney.

Western Blot: Annexin A6 Antibody [H00000309-B01P] - Analysis of ANXA6 expression in transfected 293T cell line by ANXA6 polyclonal antibody. Lane 1: ANXA6 transfected lysate(74.03 KDa). Lane 2: Non-transfected lysate.

Product Discontinued

Annexin A6 Antibody Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: ANXA6 (NP_001146.2, 1 a.a. - 673 a.a.) full-length human protein. MAKPAQGAKYRGSIHDFPGFDPNQDAEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDLIADLKYELTGKFERLIVGLMRPPAYCDAKEIKDAISGIGTDEKCLIEILASRTNEQMHQLVAAYKDAYERDLEADIIGDTSGHFQKMLVVLLQGTREEDDVVSEDLVQQDVQDLYEAGELKWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIRSTPEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTSGEYKKTLLKLSGGDDDAAGQFFPEAAQVAYQMWELSAVARVELKGTVRPANDFNPDADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTDLKSEISGDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAINEAYKEDYHKSLEDALSSDTSGHFRRILISLATGHREEGGENLDQAREDAQVAAEILEIADTPSGDKTSLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVAIVQSVKNKPLFFADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRREFIEKYDKSLHQAIEGDTSGDFLKALLALCGGED
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: ANXA6
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: It has been used for WB and Functional.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein G purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Annexin A6 Antibody

• 67 kDa calelectrin
• Annexin A6
• annexin VI (p68)
• Annexin VI
• annexin-6
• ANX6
• ANXA6
• calcium-binding protein p68
• Calelectrin
• calphobindin II
• Calphobindin-II
• CBP68
• chromobindin-20
• CPB-II
• CPB-II
• Lipocortin VI
• p68
• p70
• Protein III

Background

The Annexins constitute a family of structurally-related, relatively abundant proteins that exhibit Ca2+-dependent binding to phospholipids. Annexins function in multiple aspects of cell biology including regulation of membrane trafficking, transmembrane channel activity, inhibition of phospholipase A2, inhibition of coagulation and mediation of cell-matrix interactions. Annexin A13 is considered the original progenitor of the 12 members of vertebrate Annexins. The expression of Annexin A13 is highly tissue-specific, being expressed only in intestinal and kidney epithelial cells. This expression is associated with a highly differentiated intracellular transport function. Two alternative splicing isoforms of Annexin A13 exist, both of which bind to rafts.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Annexin A6 Antibody (H00000309-B01P)(1)

Publication using H00000309-B01P

• Ramirez-Mata A, Michalak C, Mendoza-Hernandez G et al. Annexin VI is a mannose-6-phosphate-independent endocytic receptor for bovine beta-glucuronidase. Exp Cell Res. 2011-06-06 [PMID: 21672540]

Bioinformatics

• Gene Symbol: ANXA6
• Uniprot:
  • NP_001146.2(Human)