Annexin A3 Antibody

Product Discontinued

Annexin A3 Antibody Summary

• Immunogen: Synthetic peptide, corresponding to amino acids 41-70 of Human Annexin III.
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ANXA3
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:50-1:200
  • Immunohistochemistry-Paraffin 1:50-1:200
  • Western Blot 1:500-1:1000
• Theoretical MW: 36 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Human, Mouse

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2)
• Preservative: 0.05% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for Annexin A3 Antibody

• 35-alpha calcimedin
• Annexin A3
• annexin A3,1,2-cyclic-inositol-phosphate phosphodiesterase
• Annexin III
• annexin-3
• ANXA3
• Calcimedin 35-alpha
• calcimedin 35-alpha
• Lipocortin III
• PAP-III
• Placental anticoagulant protein III
• placental anticoagulant protein III, calcimedin 35-alpha

Background

The Annexin family of calcium-binding proteins is composed of at least ten mammalian genes and is characterized by a conserved core domain, which binds phospholipids in a Ca2+-dependent manner, and a unique amino-terminal region, which may confer binding specificity. Annexin family members have been implicated as regulators of such diverse processes as ion flux, endocytosis, exocytosis and cellular adhesion. Annexin III, also known as ANXA3, Annexin A3, Lipocortin III, PAP-III (placental anticoagulant protein III), 35-alpha calcimedin or ANX3, belongs to the Annexin family and contains four Annexin repeats. Annexin III exhibits a variety of functions, including anti-coagulent properties, an inhibitory role towards phospholipase A2 (PLA2) and an enzymatic function, cleaving the cyclic bond of inositol 1,2-cyclic phosphate to produce inositol 1-phosphate.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

FAQs for Annexin A3 Antibody (NBP1-19783). (Showing 1 - 1 of 1 FAQ).

1. I am looking for mouse Anxa3 antibody suitable for immunohistochemitry, and find your antibody, Cat#: NBP1-19783, Annexin A3 polyclonal antibody. Do you have the data of WB or IHC using this antibody against mouse samples?
   • Reactivity with mouse samples for NBP1-19783 was reported by a customer, and we are not able to release their data. We will gladly guarantee NBP1-19783 for IHC and western blot on mouse samples, and if the antibody does not perform as promised we will gladly issue a refund or replacement.

Bioinformatics

• Gene Symbol: ANXA3
• Entrez:
  • 306(Human)
  • 11745(Mouse)
• Uniprot:
  • P12429()