Amyloid Oligomers Antibody - BSA Free

Western Blot: Amyloid Oligomers Antibody [NBP1-97930] - Western blot analysis of Human Abeta42 fibrils and prefibrillar oligomers showing detection of Amyloid Oligomers Oligomers (A11) protein using Rabbit Anti-Amyloid Oligomers Oligomers (A11) Polyclonal Antibody (NBP1-97930). Primary Antibody: Rabbit Anti-Amyloid Oligomers Oligomers (A11) Polyclonal Antibody (NBP1-97930) at 1:1000. Courtesy of: Kayed, R., Head, E., Thompson, J. L., McIntire, T. M., Milton, S. C., Cotman, C. W., et al. (2003). Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis. Science 300, 486-489. doi: 10.1126/science.1079469.

• Reactivity: Hu, Mu, Rt, Eu
• Applications: WB, DB, ELISA, ICC/IF, IHC, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

Amyloid Oligomers Antibody - BSA Free Summary

• Immunogen: Synthetic molecular mimic of soluble oligomers
• Localization: Membrane
• Specificity: Recognizes all types of amyloid oligomers. Appears to recognize a peptide backbone epitope that is common to amyloid oligomers, but is not found in native proteins, amyloidogenic monomer or mature amyloid fibrils.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: APP
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Dot Blot
  • ELISA 0.1-10 ug/ml
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry 1:1000-1:10000
  • Immunohistochemistry-Paraffin 1:1000-1:10000
  • Immunoprecipitation 1:1000
  • Western Blot 1:1000
• Application Notes: A 1:1000 dilution of Amyloid Oligomers (A11) Antibody was sufficient for detection of amyloid oligomers in 10 ug of mouse brain lysates by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary Antibody.

Reactivity Notes

Immunogen displays sequence identity for non-tested species: Eukaryotes.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS, 50% Glycerol
• Preservative: 0.09% Sodium Azide
• Purity: Protein A purified

Alternate Names for Amyloid Oligomers Antibody - BSA Free

• eukaryotic translation initiation factor 3 subunit p42

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Amyloid Oligomers Antibody (NBP1-97930)(1)

Publication using NBP1-97930

• Zhao Y, Qiao S, Zhang B Et al. A novel neuroinflammation-responsive hydrogel based on mimicking naked mole rat brain microenvironment retards neurovascular dysfunction and cognitive decline in Alzheimer s disease Front Aging Neurosci 2022-07-21 [PMID: 35860673] (Cytometric Bead Assay Standard)

FAQs for Amyloid Oligomers Antibody (NBP1-97930). (Showing 1 - 1 of 1 FAQ).

1. Is this antibody also known as A11 antibody? Is the same antibody as i believe originated from the Glabe lab in Califormia?
   • Yes, this antibody has some other names also like- A11, Amyloid Oligomer AlphaBeta, oligomers, amyloid, A11 antibody. It is a licensed product and yes it is the same antibody which was invented by Rakez Kayed et al from Charles Glabe Lab form University of California. You probably already know that but most of its details may be found in Kayed et al., (2007) Biomed Central: Molecular Neurodegeneration, 2: 18

Bioinformatics

• Gene Symbol: APP
• Entrez:
  • 351(Human)
• Uniprot:
  • P05067()