Amylin Antibody (C2) - BSA Free

Immunohistochemistry-Paraffin: Amylin Antibody (C2) [NBP3-41139] - DAB staining on IHC-P; Samples: Human Rectum Cancer Tissue.

Immunohistochemistry-Paraffin: Amylin Antibody (C2) [NBP3-41139] - DAB staining on IHC-P; Sample: Human Pancreas Tissue; Primary Ab: 40ug/ml NBP3-41139; Second Ab: 2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody

• Reactivity: Hu
• Applications: WB, IHC
• Clone: C2
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

Amylin Antibody (C2) - BSA Free Summary

• Description: Novus Biologicals Mouse Amylin Antibody (C2) - BSA Free (NBP3-41139) is a monoclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Immunized with Human Amylin (Uniprot#: P10997; Immunogen sequence: Lys34-Val50 (Uniprot#: P10997)
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: IAPP
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 5-40ug/mL
  • Immunohistochemistry-Paraffin 5-40ug/mL
  • Western Blot

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 0.01M PBS, pH7.4, 50% glycerol
• Preservative: 0.05% Proclin 300
• Concentration: 1 mg/ml
• Purity: Protein A or G purified

Alternate Names for Amylin Antibody (C2) - BSA Free

• AMYLIN
• DAPamylin
• Diabetes-associated peptide
• IAP
• Insulinoma amyloid peptide
• Islet amyloid polypeptide (diabetes-associated peptide; amylin)
• islet amyloid polypeptide

Background

Amylin is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the association of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Recent results suggest that amylin, like the related beta amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: IAPP