AHR Antibody (684217) [Janelia Fluor® 646]

• Reactivity: Hu
• Applications: IHC
• Clone: 684217
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Janelia Fluor 646

AHR Antibody (684217) [Janelia Fluor® 646] Summary

• Immunogen: E. coli-derived recombinant human AHR
  Asn704-Leu848
  Accession # P35869
• Specificity: Detects human AHR in direct ELISAs.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: AHR
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for AHR Antibody (684217) [Janelia Fluor® 646]

• Ah receptor
• AHR
• AH-receptor
• aryl hydrocarbon receptor
• BHLHE76
• bHLHe76aromatic hydrocarbon receptor
• Class E basic helix-loop-helix protein 76

Background

Aryl hydrocarbon receptor (AHR) is a member of the basic-helix-loop-helix transcription factor protein family that is a normally inactive cytosolic transcription factor. Upon ligand binding AhR translocates to the nucleus and dimerizes with the AhR nuclear translocator (ARNT), leading to gene transcription alterations.

AHR is expressed in all tissues and most likely plays an important role in the development and maturation of many tissues.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: AHR