AGTR-2 Antibody - BSA Free

• Reactivity: Rt
• Applications: WB, ELISA, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

AGTR-2 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit AGTR-2 Antibody - BSA Free (NBP2-89082) is a polyclonal antibody validated for use in IHC, WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Synthetic peptide corresponding to the sequence near the N-terminus of rat angiotensin II receptorAGTR-2.
• Clonality: Polyclonal
• Host: Rabbit
• Gene: AGTR2
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry
  • Western Blot

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS containing 50% glycerol
• Preservative: 0.01% Sodium Azide
• Purity: Peptide affinity purified

Alternate Names for AGTR-2 Antibody - BSA Free

• AGTR2
• AGTR-2
• Angiostensin Receptor
• angiotensin II receptor, type 2
• Angiotensin II type-2 receptor
• angiotensin receptor 2
• AT2
• AT2ATGR2
• AT2R
• MRX88
• MRX88type-2 angiotensin II receptor

Background

Angiotensin II is a potent pressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors termed AT1 and AT2. AGTR2 belongs to a family 1 of G-protein coupled receptors. It is an intergral membrane protein. It plays a role in the central nervous system and cardiovascular functions that are mediated by the renin-angiotensin system. This receptor mediates programmed cell death (apoptosis). In adults, it is highly expressed in myometrium with lower levels in adrenal gland and fallopian tube. It is highly expressed in fetal kidney and intestine. The human AGTR2 gene is composed of three exons and spans at least 5 kb. Exons 1 and 2 encode for 5; untranslated mRNA sequence and exon 3 harbors the entire uninterrupted open reading frame.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: AGTR2