AF10 Antibody (HAF10 9A5/2)

Product Discontinued

AF10 Antibody (HAF10 9A5/2) Summary

• Immunogen: Synthetic peptide: RLSDKTGPVAQEKS, corresponding to amino acids 1055-1069 of Human AF10.
• Localization: Nuclear
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: MLLT10
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • ELISA 1:100 - 1:2000
  • Flow Cytometry 1:10 - 1:1000
  • Immunohistochemistry 1:10 - 1:500
  • Immunoprecipitation 1:10 - 1:500
  • Western Blot 1:100 - 1:2000
• Application Notes: This antibody is Cytof ready.
• Control:

  AF10 Overexpression Lysate

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein A or G purified

Alternate Names for AF10 Antibody (HAF10 9A5/2)

• AF10MGC75086
• ALL1-fused gene from chromosome 10 protein
• DKFZp686E10210
• myeloid/lymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog);translocated to, 10
• myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila);translocated to, 10
• protein AF-10
• type I AF10 protein

Background

AF10 is a putative transcription factor containing a leucine zipper motif. A t(10;11)(p12;q23) chromosomal translocation present in a proportion of acute myeloid leukaemias results in expression of an AF10 (carboxy terminus) MLL (amino terminus) fusion protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MLLT10
• Entrez:
  • 8028(Human)