AF10 Products

Description

AF10 is a putative transcription factor containing a leucine zipper motif. A t(10;11)(p12;q23) chromosomal translocation present in a proportion of acute myeloid leukaemias results in expression of an AF10 (carboxy terminus) MLL (amino terminus) fusion protein.

Bioinformatics

Entrez	8028 Human 17354 Mouse 361285 Rat
Uniprot	P55197 Human NM_004641 Human NP_004632 Human NP_004632.1 Human
Product By Gene ID	8028
Alternate Names	type I AF10 protein myeloid/lymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog);translocated to, 10 protein AF-10 ALL1-fused gene from chromosome 10 protein AF10MGC75086 DKFZp686E10210 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila);translocated to, 10

Diseases related to AF10

Discover more about diseases related to AF10.

Leukemia
Myeloid Leukemia
Leukemia, Myelocytic, Acute
Chromosomal Translocation
Acute Lymphocytic Leukemia
Acute Leukemia
Leukemogenesis
Malignant Neoplasms
Acute Monocytic Leukemia
Hematologic Neoplasms
Neoplasms
Malignant Paraganglionic Neoplasm
Cytogenetic Abnormality
Lymphoma
Precursor T-cell Lymphoblastic Leukemia-lymphoma
Monoblastic Leukemia
Cell Transformation, Neoplastic
Neoplasm, Residual
Chromosome Breakage
Myeloid Leukemia, Chronic

Pathways for AF10

View related products by pathway and learn more about each of the pathways below.

Methylation
Localization
Reverse Transcription
Interphase
Histone Methylation
Cell Adhesion
Clathrin-mediated Endocytosis
Transposition
Cell Cycle Checkpoint
Gene Silencing
Dna Repair
Regulation Of Gene Expression
Endocytosis
Nuclear Export
Cell Cycle
Cell Communication
Angiogenesis
Chromatin Assembly
Histone H3-k79 Methylation
Chromatin Remodeling

PTMs for AF10

Learn more about PTMs related to AF10.

Methylation
Phosphorylation
Reduction

Bioinformatics Tool for AF10

Discover related pathways, diseases and genes to AF10. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.