AdipoR1 Antibody (2416C) [Alexa Fluor™ Plus 488]

• Reactivity: Hu
• Clone: 2416C
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Alexa Fluor Plus 488

AdipoR1 Antibody (2416C) [Alexa Fluor™ Plus 488] Summary

• Specificity: Detects human AdipoR1 in direct ELISAs. In direct ELISA, no cross-reactivity with human AdipoR2 is observed
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Rabbit

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for AdipoR1 Antibody (2416C) [Alexa Fluor™ Plus 488]

• ACDCR1
• adiponectin receptor 1
• adiponectin receptor protein 1
• AdipoR1
• ADR1
• CGI45
• FLJ42464
• PAQR1
• PAQR1FLJ25385
• Progestin and adipoQ receptor family member I
• TESBP1A

Background

Adiponectin receptor protein 1 (AdipoR1) is a 7 transmembrane receptor for globular and full-length adiponectin required for normal glucose and fat homeostasis and for maintaining a normal body weight.  AdipoR1 mediates increased AMP kinase and PPAR-alpha ligand activities well as fatty-acid oxidation and glucose uptake by adiponectin.  Genetic variability at the AdipoR1 locus is a strong determinant of coronary artery disease susceptibility in type 2 diabetes.  AdipoR1 is abundantly expressed in skeletal muscle.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.