ADAMTS5 Antibody

Images

 
Western Blot: ADAMTS5 Antibody [NBP2-15286] - Sample (30 ug of whole cell lysate) A: HeLa B: HepG2 7. 5% SDS PAGE, antibody diluted at 1:3000.
Immunohistochemistry-Paraffin: ADAMTS5 Antibody [NBP2-15286] - Paraffin-embedded Hepatoma, using antibody at 1:500 dilution.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

ADAMTS5 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human ADAMTS5. The exact sequence is proprietary.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ADAMTS5
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
  • Immunohistochemistry 10 - 1:500
  • Immunohistochemistry-Paraffin 1:100-1:1000
Theoretical MW
102 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.0), 1.0% BSA and 20% Glycerol
Preservative
0.01% Thimerosal
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for ADAMTS5 Antibody

  • A disintegrin and metalloproteinase with thrombospondin motifs 11
  • a disintegrin-like and metalloprotease (reprolysin type) with thrombospondintype 1 motif, 5 (aggrecanase-2)
  • ADAM metallopeptidase with thrombospondin type 1 motif, 5
  • ADAM-TS 11
  • ADAM-TS 5
  • ADAMTS11
  • ADAMTS-11
  • ADAMTS5
  • ADAM-TS5
  • ADAMTS-5
  • ADMP2
  • ADMP-2
  • ADMP-2A disintegrin and metalloproteinase with thrombospondin motifs 5
  • Aggrecanase 2
  • aggrecanase-2
  • disintegrin-like and metalloprotease with thrombospondin type 1 motif, 510ADAMTS11FLJ36738
  • EC 3.4.24
  • EC 3.4.24.-
  • EC 3.4.24.14
  • EC 3.4.24.82

Background

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs and functions as aggrecanase to cleave aggrecan, a major proteoglycan of cartilage. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol ADAMTS5
Entrez
Uniprot