ADAMTS5 Products

Antibodies
ADAMTS5 Antibody
ADAMTS5 Antibody
NBP2-15286
Species: Hu, Mu, Rt, Bv
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
ADAMTS5 Antibody
ADAMTS5 Antibody
NLS7761
Species: Hu, Mu, Rt, Bt, Ca, Eq, Ha, Pm, Pm, Po
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
ADAMTS5 Antibody (362810)
ADAMTS5 Antibody (362810)
MAB2198
Species: Hu
Applications: WB, IP
Host: Mouse Monoclonal
Formulation Catalog # Availability Price  
ELISA Kits
Human ADAMTS5 DuoSet ELISA, 5 ...
Human ADAMTS5 DuoSet ELISA, 5 Plate
DY2198-05
Species: Hu
Applications: ELISA
Human ADAMTS5 ELISA Kit (Colo ...
Human ADAMTS5 ELISA Kit (Colorimet...
NBP2-66444
Species: Hu
Applications: ELISA
Proteins
Recombinant Human ADAMTS5 Pro ...
Recombinant Human ADAMTS5 Protein, CF
2198-AD
Species: Hu
Applications: Enzyme Activity
Formulation Catalog # Availability Price  
ADAMTS5 Recombinant Protein A ...
ADAMTS5 Recombinant Protein Antigen
NBP2-55654PEP
Species: Hu
Applications: AC
ADAMTS5 Recombinant Protein A ...
ADAMTS5 Recombinant Protein Antigen
NBP2-55653PEP
Species: Hu
Applications: AC

Description

ADAMTS5, also known as aggrecanase-2, is a Metallopeptidase M12B type protease that is responsible for degradation of the articular cartilage protein aggrecan. The protein contains a signal sequence, a prodomain with both a potential cysteine switch and a furin cleavage site, a metalloproteinase domain with a conserved zinc-binding motif and a 'met turn,' a disintegrin-like domain, and a spacer region between a thrombospondin type 1 motif and thrombospondin submotif. At least four transcript variants have been reported. ADAMTS5 has been implicated in inflammatory joint diseases. ADAMTS5 expression has been documented in a range of normal human tissues. ESTs have been isolated from human tissue libraries, including normal breast, embryo and heart and cancerous placenta and uterus.

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 11096
Alternate Names
  • EC 3.4.24.82
  • ADAM-TS 5
  • EC 3.4.24.14
  • ADAM-TS 11
  • EC 3.4.24
  • ADAMTS-5
  • EC 3.4.24.-
  • ADAMTS-11
  • Aggrecanase-2
  • ADAM-TS5
  • ADMP2
  • A disintegrin and metalloproteinase with thrombospondin motifs 11
  • aggrecanase-2
  • a disintegrin-like and metalloprotease (reprolysin type) with thrombospondintype 1 motif, 5 (aggrecanase-2)
  • ADMP-2A disintegrin and metalloproteinase with thrombospondin motifs 5
  • disintegrin-like and metalloprotease with thrombospondin type 1 motif, 510ADAMTS11FLJ36738
  • ADAM metallopeptidase with thrombospondin type 1 motif, 5

Research Areas for ADAMTS5

Find related products by research area and learn more about each of the different research areas below.

GPCR

Bioinformatics Tool for ADAMTS5

Discover related pathways, diseases and genes to ADAMTS5. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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