ADAMTS5 Products

Antibodies
ADAMTS5 Antibody [Unconjugate ...
ADAMTS5 Antibody [Unconjugated]
AF2198
Species: Hu
Applications: WB, IP
Host: Goat Polyclonal
ADAMTS5 Antibody (362810)
ADAMTS5 Antibody (362810)
MAB2198
Species: Hu
Applications: WB, IP
Host: Mouse Monoclonal
ADAMTS5 Antibody
ADAMTS5 Antibody
NBP1-89247
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
ADAMTS5 Overexpression Lysate ...
ADAMTS5 Overexpression Lysate (Nat...
NBL1-07317
Applications: WB
Proteins
ADAMTS5 Recombinant Protein A ...
ADAMTS5 Recombinant Protein Antigen
NBP1-89247PEP
Species: Hu
Applications: AC
ADAMTS5 Recombinant Protein
ADAMTS5 Recombinant Protein
P4931
Species: Hu
Applications: Func, PAGE
RNAi
ADAMTS5 RNAi
ADAMTS5 RNAi
H00011096-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

ADAMTS5, also known as aggrecanase-2, is a Metallopeptidase M12B type protease that is responsible for degradation of the articular cartilage protein aggrecan. The protein contains a signal sequence, a prodomain with both a potential cysteine switch and a furin cleavage site, a metalloproteinase domain with a conserved zinc-binding motif and a 'met turn,' a disintegrin-like domain, and a spacer region between a thrombospondin type 1 motif and thrombospondin submotif. At least four transcript variants have been reported. ADAMTS5 has been implicated in inflammatory joint diseases. ADAMTS5 expression has been documented in a range of normal human tissues. ESTs have been isolated from human tissue libraries, including normal breast, embryo and heart and cancerous placenta and uterus.

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 11096
Alternate Names
  • EC 3.4.24.82
  • ADAM-TS 5
  • EC 3.4.24.14
  • ADAM-TS 11
  • EC 3.4.24
  • ADAMTS-5
  • EC 3.4.24.-
  • ADAMTS-11
  • Aggrecanase-2
  • ADAM-TS5
  • ADMP2
  • A disintegrin and metalloproteinase with thrombospondin motifs 11
  • aggrecanase-2
  • a disintegrin-like and metalloprotease (reprolysin type) with thrombospondintype 1 motif, 5 (aggrecanase-2)
  • ADMP-2A disintegrin and metalloproteinase with thrombospondin motifs 5
  • disintegrin-like and metalloprotease with thrombospondin type 1 motif, 510ADAMTS11FLJ36738
  • ADAM metallopeptidase with thrombospondin type 1 motif, 5

Research Areas for ADAMTS5

Find related products by research area and learn more about each of the different research areas below.

GPCR

Bioinformatics Tool for ADAMTS5

Discover related pathways, diseases and genes to ADAMTS5. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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