Gorilla, Orangutan, Gibbon, Marmoset. Predicted cross-reactivity based on sequence identity: Elephant (94%), Bat (88%), Porcine (88%), Rat (82%), Hamster (82%), Rabbit (82%). Mouse reactivity reported in scientific literature (PMID: 24260246).
Alternate Names for ADAMTS1 Antibody
a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two disintegrin loops and three C-terminal TS motifs and has anti-angiogenic activity. The expression of this gene may be associated with various inflammatory processes as well as development of cancer cachexia. This gene is likely to be necessary for normal growth, fertility, and organ morphology and function.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.