ADAMTS1 Antibody - BSA Free

Immunohistochemistry-Paraffin: ADAMTS1 Antibody - BSA Free [NBP1-50161] - Analysis of anti-ADAMTS1 antibody with human testis, vessels.

• Reactivity: Hu, Mu, Pm, Pm, Pm-Or
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

ADAMTS1 Antibody - BSA Free Summary

• Description: Product can be stored undiluted at 4C for up to 1 month.
• Immunogen: Synthetic 17 amino acid peptide from internal region of human ADAMTS1.
• Epitope: Internal region
• Specificity: Human ADAMTS1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Orangutan (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ADAMTS1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 20ug/ml
  • Immunohistochemistry-Paraffin 20 ug/ml
• Application Notes: .

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (100%), Bat (88%), Porcine (88%), Mouse (82%), Rat (82%), Hamster (82%), Rabbit (82%). Use in Mouse reported in scientific literature (PMID:24260246).

Packaging, Storage & Formulations

• Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for ADAMTS1 Antibody - BSA Free

• a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 1
• ADAM metallopeptidase with thrombospondin type 1 motif, 1
• ADAM-TS 1
• ADAMTS1
• ADAM-TS1
• ADAMTS-1
• C3-C5
• METH1
• METH-1

Background

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two disintegrin loops and three C-terminal TS motifs and has anti-angiogenic activity. The expression of this gene may be associated with various inflammatory processes as well as development of cancer cachexia. This gene is likely to be necessary for normal growth, fertility, and organ morphology and function.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for ADAMTS1 Antibody (NBP1-50161)(1)

Publication using NBP1-50161

• Development of a Reactive Stroma Associated With Prostatic Intraepithelial Neoplasia in EAF2 Deficient Mice Pascal L, Ai J, Masoodi K et al. PLoS One. [PMID: 24260246] (IHC-P, Mouse)

Bioinformatics

• Gene Symbol: ADAMTS1
• Entrez:
  • 9510(Human)
• Uniprot:
  • Q9UHI8()