Activin RIA/ALK-2/Activin Receptor Type 1 Antibody (2E2C11)

Images

 
Western Blot: Activin RIA/ALK-2/Activin Receptor Type 1 Antibody (2E2C11) [NBP2-61799] - Analysis using ACVR1 mAb against human ACVR1 (AA: 21-120) recombinant protein. (Expected MW is 37.1 kDa)
Immunocytochemistry/ Immunofluorescence: Activin RIA/ALK-2/Activin Receptor Type 1 Antibody (2E2C11) [NBP2-61799] - Analysis of Hela cells using ACVR1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin ...read more
Immunohistochemistry-Paraffin: Activin RIA/ALK-2/Activin Receptor Type 1 Antibody (2E2C11) [NBP2-61799] - Analysis of endometrial cancer tissues using ACVR1 mouse mAb with DAB staining.
Western Blot: Activin RIA/ALK-2/Activin Receptor Type 1 Antibody (2E2C11) [NBP2-61799] - Analysis using ACVR1 mAb against HEK293 (1) and ACVR1 (AA: 21-120)-hIgGFc transfected HEK293 (2) cell lysate.
Immunocytochemistry/ Immunofluorescence: Activin RIA/ALK-2/Activin Receptor Type 1 Antibody (2E2C11) [NBP2-61799] - Analysis of Hela cells using ACVR1 mouse mAb. Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments ...read more
Immunohistochemistry-Paraffin: Activin RIA/ALK-2/Activin Receptor Type 1 Antibody (2E2C11) [NBP2-61799] - Analysis of ovarian cancer tissues using ACVR1 mouse mAb with DAB staining.
ELISA: Activin RIA/ALK-2/Activin Receptor Type 1 Antibody (2E2C11) [NBP2-61799] - Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
ELISA: Activin RIA/ALK-2/Activin Receptor Type 1 Antibody (2E2C11) [NBP2-61799] - Analysis of Hela cells using ACVR1 mouse mAb (green) and negative control (red).

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, Flow, ICC/IF, IHC, IHC-P
Clone
2E2C11
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

Activin RIA/ALK-2/Activin Receptor Type 1 Antibody (2E2C11) Summary

Immunogen
Purified recombinant fragment of human ACVR1 (AA: 21-120) expressed in E. Coli.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
ACVR1
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:2000
  • ELISA 1:10000
  • Flow Cytometry 1:200-1:400
  • Immunocytochemistry/Immunofluorescence 1:10-1:500
  • Immunohistochemistry 1:200-1:1000
  • Immunohistochemistry-Paraffin 1:200-1:1000
Theoretical MW
57.2 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.05% Sodium Azide
Concentration
1 mg/ml
Purity
Protein G purified

Alternate Names for Activin RIA/ALK-2/Activin Receptor Type 1 Antibody (2E2C11)

  • activin A receptor, type I
  • Activin RIA
  • ActivinRIA
  • ACTRI
  • ACVR1
  • ACVR1A
  • ACVRLK2
  • ALK2
  • ALK-2
  • FOP
  • SKR1
  • TSRI

Background

Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Activin RIA/ALK-2/Activin Receptor Type 1 Antibody (NBP2-61799) (0)

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Bioinformatics

Gene Symbol ACVR1